For actual talents i would say melee defense, you can never have too much melee defense :P
For perks, i would say brawny and erm the first tier one to the most right was it, student? The one that gives you exp bonus and a perk when you level up, thats probably one of the best perks in game. Apart form that you want a weapon specialization, you want the underdog, the one that gives additional fear on strikes and the one that gives hit chance to the head. After that youre pretty much set.